
Taming the Piers-Rubinsztajn Reaction: Beyond B(C6F5)3
D. Wilson, R. Maar, A.-C. Bédard, S. Mukhopadhyay, H. Spinney*, M.-A. Courtemanche* Organometallics 2025, 44, 2777-2785

Development of the “Phase Separation” Strategy: Addressing Dilution Effects in Macrocyclization
S. K. Collins*, A.-C. Bédard, É. Godin, M. Raymond, M. de Léséleuc, S. Parisien-Collette, S. Régnier, J. Santandrea, and M. Holtz-Mulholland Canadian Journal of Chemistry 2025, 103, 465-479
Reconfigurable system for automated optimization of diverse chemical reactions

A.-C. Bédard, A. Adamo, KC Aroh, MG Russell, AA Bedermann, J. Torosian, B. Yue, KF Jensen*, TF Jamison* Science 2018 , 361 , 1220-1225.

H. Seo, A.-C. Bédard, WP Chen, RW Hicklin, A. Alabugin, TF Jamison* Tetrahedron , 2018 , 74 , 3124-3128.
Selective
N-monomethylation of primary anilines with dimethyl carbonate in continuous flow
Phase Separation Macrocyclization in a Complex Pharmaceutical Setting: Application toward the Synthesis of Vaniprevir

E. Godin, A.-C. Bédard, M. Raymond et SK Collins* Journal of Organic Chemistry , 2017 , 82 , 7576‑7582.

Minimizing E-factor in the continuous-flow synthesis of diazepam and atropine
A.-C. Bédard, A R. Longstreet, J. Britton, Y. Wang, H. Moriguchi, RW Hicklin, WH Green et TF Jamison* Bioorganic & Medicinal Chemistry 2017 , 25 , 6233–6241.
Efficient Continuous-Flow Synthesis of Macrocyclic Triazoles

A.-C. Bédard, J. Santandrea et SK Collins*
Journal of Flow Chemistry , 2015 , 5 , 142‑144.

A.-C. Bédard et SK Collins* Organic Letters , 2014 , 16 , 5286‑5289
Advanced Strategies for Efficient Macrocyclic Cu(I)-Catalyzed Cycloaddition of Azides
Macrocyclic Cu(I)-Catalyzed Sonogashira Cross-Coupling

A.-C. Bédard et SK Collins* Organic Letters , 2014 , 16 , 5286‑5289

I. Dion, J.-F. Vincent-Rocan, L. Zhang, PH Cebrowsky, M.-E. Lebrun, JY Yael, A.-C. Bédard et AM Beauchemin* Journal of Organic Chemistry , 2013 , 78 , 12735‑12749.
Studies on Difficult Intramolecular Hydroaminations in the Context of Four Syntheses of Alkaloid Natural Product
Synthesis, Crystal Structure and Photophysical Properties of Pyrene–Helicene Hybrids
A.-C. Bédard, A. Vlassova, AC Hernandez-Perez, A. Bessette, GS Hanan, MA Heuft et SK Collins* Chemistry – A European Journal , 2013 , 19 , 16295‑16302.

Continuous Flow Macrocyclization at High Concentrations: Synthesis of Macrocyclic Lipids
A.-C. Bédard, S. Regnier and S. K. Collins*
Green Chemistry, 2013, 15, 1962‑1966

Influence de la structure du poly(éthylène glycol) sur les réactions de macrocyclisation catalytique
A.-C. Bédard et SK Collins* ACS Catalysis , 2013 , 3 , 773‑782.

Exploiting Aggregation To Achieve Phase Separation in Macrocyclization

A.-C. Bédard and S. K. Collins*
Chemistry – A European Journal, 2013, 19, 2108‑2113.
Microwave accelerated Glaser–Hay macrocyclizations at high concentrations
A.-C. Bédard et SK Collins*
Chemical Communications , 2012 , 48 , 6420‑6422


A.-C. Bédard and S. K. Collins*
Journal of the American Chemical Society, 2011, 133, 19976‑19981.
Phase Separation As a Strategy Toward Controlling Dilution Effects in Macrocyclic Glaser-Hay Couplings
The Tandem Cope-Type Hydroamination/[2,3]-Rearrangement Sequence: A Strategy to Favor the Formation of Intermolecular Hydroamination Products and Enable Difficult Cyclizations
J. Bourgeois, I. Dion, P. H. Cebrowsky, F. Loiseau, A.-C. Bédard, and A. M. Beauchemin*
Journal of the American Chemical Society, 2009, 131, 874‑875.


J. Moran, SI Gorelsky, M.-E. Lebrun, A.-C. Bédard, C. Séguin et AM Beauchemin*
Journal de la Société américaine de chimie , 2008 , 130 , 17893‑17906.
Intermolecular Cope-Type Hydroamination of Alkenes and Alkynes using Hydroxylamines
A rare ligand bridged ferromagnetically coupled MnIV3 complex with a ground spin state of S = 9/2

Pathmalingam, SI Gorelsky, TJ Burchell, A.-C. Bédard, AM Beauchemin*, R. Clérac et M. Murugesu* Chemical Communications , 2008 , 2782‑2784.

