Taming the Piers-Rubinsztajn Reaction: Beyond B(C6F5)3
D. Wilson, R. Maar, A.-C. Bédard, S. Mukhopadhyay, H. Spinney*, M.-A. Courtemanche* Organometallics 2025, 44, 2777-2785
Development of the “Phase Separation” Strategy: Addressing Dilution Effects in Macrocyclization
S. K. Collins*, A.-C. Bédard, É. Godin, M. Raymond, M. de Léséleuc, S. Parisien-Collette, S. Régnier, J. Santandrea, and M. Holtz-Mulholland Canadian Journal of Chemistry 2025, 103, 465-479
Reconfigurable system for automated optimization of diverse chemical reactions
A.-C. Bédard, A. Adamo, K. C. Aroh, M. G. Russell, A. A. Bedermann, J. Torosian, B. Yue, K. F. Jensen*, T. F. Jamison* Science 2018, 361, 1220-1225.
H. Seo, A.-C. Bédard, W. P. Chen, R. W. Hicklin, A. Alabugin, T. F. Jamison* Tetrahedron, 2018, 74, 3124-3128.
Selective
N-monomethylation of primary anilines with dimethyl carbonate in continuous flow
Phase Separation Macrocyclization in a Complex Pharmaceutical Setting: Application toward the Synthesis of Vaniprevir
E. Godin, A.-C. Bédard, M. Raymond and S. K. Collins* Journal of Organic Chemistry, 2017, 82, 7576‑7582.
Minimizing E-factor in the continuous-flow synthesis of diazepam and atropine
A.-C. Bédard, A R. Longstreet, J. Britton, Y. Wang, H. Moriguchi, R. W. Hicklin, W. H. Green and T. F. Jamison* Bioorganic & Medicinal Chemistry 2017, 25, 6233–6241.
Efficient Continuous-Flow Synthesis of Macrocyclic Triazoles
A.-C. Bédard, J. Santandrea and S. K. Collins*
Journal of Flow Chemistry, 2015, 5, 142‑144.
A.-C. Bédard and S. K. Collins* Organic Letters, 2014, 16, 5286‑5289
Advanced Strategies for Efficient Macrocyclic Cu(I)-Catalyzed Cycloaddition of Azides
Macrocyclic Cu(I)-Catalyzed Sonogashira Cross-Coupling
A.-C. Bédard and S. K. Collins* Organic Letters, 2014, 16, 5286 ‑5289
I. Dion, J.-F. Vincent-Rocan, L. Zhang, P. H. Cebrowsky, M.-E. Lebrun, J. Y. Yael, A.-C. Bédard, and A. M. Beauchemin* Journal of Organic Chemistry, 2013, 78, 12735‑12749.
Studies on Difficult Intramolecular Hydroaminations in the Context of Four Syntheses of Alkaloid Natural Product
Synthesis, Crystal Structure and Photophysical Properties of Pyrene–Helicene Hybrids
A.-C. Bédard, A. Vlassova, A. C. Hernandez-Perez, A. Bessette, G. S. Hanan, M. A. Heuft and S. K. Collins* Chemistry – A European Journal, 2013, 19, 16295‑16302.
Continuous Flow Macrocyclization at High Concentrations: Synthesis of Macrocyclic Lipids
A.-C. Bédard, S. Regnier and S. K. Collins*
Green Chemistry, 2013, 15, 1962‑1966
Influence of Poly(ethylene glycol) Structure in Catalytic Macrocyclization Reactions
A.-C. Bédard and S. K. Collins* ACS Catalysis, 2013, 3, 773‑782.
Exploiting Aggregation To Achieve Phase Separation in Macrocyclization
A.-C. Bédard and S. K. Collins*
Chemistry – A European Journal, 2013, 19, 2108‑2113.
Microwave accelerated Glaser–Hay macrocyclizations at high concentrations
A.-C. Bédard and S. K. Collins*
Chemical Communications, 2012, 48, 6420‑6422
A.-C. Bédard and S. K. Collins*
Journal of the American Chemical Society, 2011, 133, 19976‑19981.
​Phase Separation As a Strategy Toward Controlling Dilution Effects in Macrocyclic Glaser-Hay Couplings
The Tandem Cope-Type Hydroamination/[2,3]-Rearrangement Sequence: A Strategy to Favor the Formation of Intermolecular Hydroamination Products and Enable Difficult Cyclizations
J. Bourgeois, I. Dion, P. H. Cebrowsky, F. Loiseau, A.-C. Bédard, and A. M. Beauchemin*
Journal of the American Chemical Society, 2009, 131, 874‑875.
J. Moran, S. I. Gorelsky, M.-E. Lebrun, A.-C. Bédard, C. Séguin and A. M. Beauchemin*
Journal of the American Chemical Society, 2008, 130, 17893‑17906.
Intermolecular Cope-Type Hydroamination of Alkenes and Alkynes using Hydroxylamines
A rare ligand bridged ferromagnetically coupled MnIV3 complex with a ground spin state of S = 9/2
Pathmalingam, S. I. Gorelsky, T. J. Burchell, A.-C. Bédard, A. M. Beauchemin*, R. Clérac and M. Murugesu* Chemical Communications, 2008, 2782‑2784.